Not in your example. The first ii is used as a passing chord.
The tune's form is I,(passing chords to get to

iii,(more passing chords to

VI, then ii,V,I, and V (as a turnaround) to get back to the top.
So, in summary, This song (simplified) is I,iii,VI,ii,V,I.
When using roman numerals, lower-case means minor, V is assumed to be a dominant 7th, and I is a major seventh.
The circle of fifths is all about "getting back home". Every dominant seventh is another note's "V"....and so on 'til you get home.

)BOB